Dr. Shazia Kousar

Assistant Professor

Ph.D., (ICCBS), Split PhD Program (UCR, USA)

Research Interests

• Synthetic Organic Chemistry, New Methodology Development, Organometallic Chemistry, Natural Product Chemistry, Carbene chemistry, Catalysis

Biography

• Shazia Kousar is serving as Assistant Professor of Chemistry at Khawaja Fareed University of Engineering and Information Technology (KFUEIT) Rahim Yar Khan. In 2000-2002, she received her BSC and MSc degree in Chemistry from Islamia University Bahawalpur, respectively. She did MSc thesis on Pyrazole ipso substitution. In 2004, joined HEJ Research Institute of Chemistry, (ICCBS) in the MS leading to PhD Program under and found potent inhibitors of α-Glucosidase enzymes did pioneer work on the Solid Phase Synthesis. University of Karachi, Pakistan.
•  In 2006, she joined the laboratory of Prof. Dr. Guy Bertrand and derived the mechanism of entirely new reaction for the formation of allene from enamine and terminal alkynes published in PNAS 2007. Continuation of work published in Chem.Eur.J. Based on this work a big literature is increasing day by day for scientific community.
•  In 2009, as postdoctoral fellow work on Harmine, Harmaline, Menthol projects. Some of her work is published in RSC advances 2015. In 2011-2013 worked as assistant professor in GCUF and supervise graduate and undergraduate students in Suzuki coupling reactions, Metal Complexes synthesis and synthetic modification of Tryptamine and Glycyrrhetinic acid, biologically active compounds. Supervise two MPhil students.
• She has excellent expertise in Glove Box, UV, IR, 1D, 2D NMR, MS, Schlenk Techniques, Handling of air sensitive compounds, structure elucidation. SAR studies, Chromatography.
  Research Interest: Her research interests are biologically active compounds in the field of organic synthesis, heterocyclic chemistry, natural products, organometallic Chemistry, stable Carbene, catalysis, medicinal Chemistry, bioassay studies, nanotechnology, biotechnology, material sciences and neurotransmitters.

Awards and Honors

• Honors: Junior and senior Fellowship by HEJ (ICCBS). PhD Fellowship Award under Split PhD program by HEC. 0.5 Million Project by HEC under IPFP programme.11 national and international publications with good scientific impact. National, International presentation to present her work at national and international level. ACS Member.

Publications

• V. Lavallo, G.D. Frey, S. Kousar, B. Donnadieu, G. Bertrand, Allene formation by gold catalyzed cross coupling of masked carbenes and vinylidenes  Proc. Natl. Acad. Sci. USA 2007, 104, 13569-13573.

Impact Factor (9.67)

• G.D. Frey, R.D. Dewhurst, S. Kousar, B. Donnadieu, G. Bertrand, Cyclic (alkyl)(amino)carbene gold(I) complexes: A synthetic and structural investigation, J. Organomet. Chem. 2008, 693 (Special Issue), 1674-1682.

Impact Factor (2.17)

• Xiaoming Zeng, Guido D. Frey, Shazia Kousar, Guy Bertrand A Cationic Gold(I) Complex as a General Catalyst for the Intermolecular Hydroamination of Alkynes: Application to the One-Pot Synthesis of Allenes from Two Alkynes and a Sacrificial Amine,Chemistry--A European Journal 2009, 15(13), 3056-3060.

Impact Factor (5.73)

• Iftikhar Hussain Bukhari, Tasmiah Batool, Muhammad Riaz, Shazia Kousar Synthesis and Spectroscopic Characterization of Transition Metal Complexes of Methyl and Methoxy substituted 2-SulfamoylbenzamidesInternational Journal of Pharmaceutical Chemistry2013, 03(02), 32-39.

• Iftikhar Hussain Bukhari,* Nabila Rasul, Shazia Kausar, Syed Ali Raza Naqvi, Zulfiqar Ali, Muhammad Riaz Comparative Studies of Ni, Cd, Mn, Co, Pb, Cr and Zn in Hair, Nail and Plasma of Smokers and Non-smokers Subjects of Sargodha Zone  International Journal of Chemical and Biochemical Sciences, 2013, 4, 28-37.

• *Qurat-ul-ain, Iftikhar Hussain Bukhari, Shazia Kousar and Jeveria Rehman Determination Of Trace Toxic Elements in Beauty Creams and Sun Blocks Using AAS and ICP-AES Spectroscopic Techniques World Journal of Pharmaceutical Research, 2013, 2(5), 1298-1305.

• Solat Perveen, Iftikhar Hussain Bukhari, Qurat-Ul-Ain, Shazia Kousar, & Jeveria Rehman Antimicrobial, Antioxidant and Minerals Evaluation of CUSCUTA EUROPEA and CUSCUTA REFLEXA Collected from Different Hosts and Exploring Their Role as Functional Attribute International Research Journal of Pharmaceutical and Applied Sciences  2013, 3(5), 43-49.

• Yasmeen Gull, Nasir Rasool*, Mnaza Noreen, Faiz-ul-Hassan Nasim, Asma Yaqoob, Shazia Kousar, Umer Rashid *, Iftikhar Hussain Bukhari, Muhammad Zubair, Md Saiful Islam.  Efficient Synthesis of 2-Amino-6-Arylbenzothiazoles via Pd(0), Suzuki Cross Coupling Reaction: Potent Urease Enzyme Inhibition and Nitric Oxide Scavenging Activities of the Products. Molecule 2013, 18, 8845-8857. Impact Factor (2.42)

• Mnaza Noreen , Nasir Rasool*, Yasmeen Gull , Faiz-ul-Hassan Nasim , Ameer Fawad Zahoor, Asma Yaqoob , Shazia Kousar , Muhammad Zubair, Iftikhar Hussain Bukhari, Usman Ali Rana. A Facile synthesis of new 5-aryl-thiophene bearing sulfonamide moiety via Pd (0)-catalyzed Suzuki-Miyaura cross coupling reactions and 5-bromothiophene-2-acetamide: As potent urease inhibitor, antibacterial agent and hemolytically active compounds. Journal of Saudi Chemical Society 2014. Impact Factor (2.52)

• Maria Aqeel Khan , Saba Fazal-ur-Rehman , Abdul Hameed , Shazia Kousar , Kourosh Dalvandi , Sammer Yousuf ,  Muhammad Iqbal Choudhary , Fatima Zehra BashaRegioselective Synthesis of Novel 2,3,4,4a-tetrahydro-1H-carbazoles and their Cholinesterase Inhibitory Activities.  Rsc Advances06. 2015; 5(73). Impact Factor (3.84)

• Kiran Aftab, Kinza Aslam, Shazia Kousar and Muhammad Jawad Ul Hasan Nadeem Synthesis, characterization and biological evaluation of tryptamine based benzamide derivativesPak. J. Pharm. Sci., 29, 2016, 423-428. Impact Factor (0.682)

• Shazia Kousar^*, Sadia Noreen Anjum, Farrukh Jaleel, Jallat Khan and Sidra NaseemBiomedical Significance of Tryptamine: A Review Journal of Pharmacovigilance 2017, Vol 5(5): 239.

• Farzana Shaheen, Shazia Kousar, Shamsun Nahar Khan, Faiza Tahir, Muhammad Zeeshan, M. Iqbal Choudhary and Atta-ur-Rahman 18β-Glycyrrhetinic Acid Derivatives as Highly Potent α-Glucosidase and Butyrylcholinesterase Inhibitors Medicinal Chemistry (preparation).

Affiliations

• ACS Member
• Member of Lab equipment procurement Committee, Planning Committee, Academic Review Committee.