Faculty Profile

Dr. Munawar Hussain
Associate Professor

  • From the early days of my childhood when everything around me was just to astonish and flood my mind, heart and eyes with huge stream of questions till now when I am 41 years old I feel nothing has changed but learned a bit to make better questions. Due to finance, after each School/Board/University Examination I always had to face a question whether there was a way left to keep going forward in education or have to quit education: similarly, whenever I started any research project I had to face a question whether it will work or not but fortunately always I found a way forward in education and research projects worked too. In my life Karachi had been a big source of education, encouragement, professionalism and many friends where I received my Master’s degree in 2002 and served in DSU for more than 4 years. I spent 02 years in Canada (International Visiting Scientist), 03 years in Germany (earned PhD) & 02 years in Sweden (Post Doctoral) too but the city where I spent my childhood and adulthood until graduation in 1999 Khanpur & Rahim Yar Khan remained with me doesn’t matter wherever I stayed. During my research career I had chance to work with Dr. Zaheer Ahmad (HEJ), Prof. Scott Dulong Taylor (Canada), Prof Peter Langer (Germany) & Prof. Fredrik Almqvist (Sweden).
  • Habit to read books but can only be satisfied when I start it from preface till the last word of the book content. The interest resulted in the reading of a big variety of books from philosophy, religion, poetry, literature, history, science and among human writings the inspiration & satisfaction by Ihya Ul Uloom by Imam Ghazali was incomparable.

It is fact that I can never stay away from research but always looking for ways to contribute substantially in the building of infrastructure of chemical manufacturing industry in Pakistan.

  1. Syed Adnan Ali Shah, Huey Ling Tan, Sadia Sultan, Muhammad Afifi Bin Mohd Faridz, Mohamad Azlan Bin Mohd Shah, Sharifah Nurfazilah, Munawar Hussain. Microbial-Catalyzed Biotransformation of Multifunctional Triterpenoids Derived from PhytonutrientsInt. In.t. J. Mol. Sci. 2014, 15 (link:http://www.mdpi.com/1422-0067/15/7/12027).

 

  1. Syed Adnan Ali Shah, Sadia Sultan, Normahanim Binti Hassan, Fauzia Khadija Binti Muhammad Muhammad Afifi Bin Mohd Faridz, Fatimah BeBe M. Hussain, Munawar Hussain, Humera Syed Adnan. Biotransformation of 17a-ethynyl substituted steroidal drugs with microbial and plant cell cultures: A review, Steroids, 2013, 78, 1312. (link: http://www.ncbi.nlm.nih.gov/pubmed/24135562).

 

  1. Munawar Hussain, Nguyen Thai Hung, Naeem Abbas, Rasheed Ahmad Khera, Imran Malik, Tamás Patonay, Nazken Kelzhanova, Zharylkasyn A. Abilov, Alexander Villinger, Peter Langer.Synthesis of Arylated Benzofurans by Regioselective Suzuki-Miyaura Cross-Coupling Reactions of 2,3-Di- and 2,3,5-Tribromobenzofurans.J. Heterocycl. Chem., 2013 (ACCEPTED) (link: http://onlinelibrary.wiley.com/doi/10.1002/jhet.2083/full).
  2. Muhammad Farooq Ibad, Dhafer Saber Zinad,Munawar Hussain,Asad Ali,Alexander Villinger, Peter Langer.One-Pot Synthesis of Arylated 1-Methyl-1H-indoles by Suzuki-Miyaura Cross-Coupling Reactions of 2,3-Dibromo-1-methyl-1H-indole and 2,3,6-Tribromo-1-methyl-1H-indole. Tetrahedron, 2013, 69, 7492. (link: http://www.sciencedirect.com/science/article/pii/S0040402013008545).
  3. Omer A. Akrawi, Afsar Khan, Munawar Hussain, Hamid H. Mohammed, Alexander Villinger, Peter Langer. Synthesis of 2,3-diarylfluorenones by domino ′twofold Heck / electrocyclization / dehydrogenation′ reactions of 2,3-dibromoindenone. Tetrahedron Lett. 2013, 54, 3037. (link: http://www.sciencedirect.com/science/article/pii/S0040403913003924).
  4. Munawar Hussain, Thomas Sainte-Luce Banchelin, Hans Andersson, Roger Olsson, and Fredrik Almqvist. Enantioselective synthesis of aryl substituted piperidines by addition of aryl Grignard reagents to pyridine N‑Oxides, Organic Letters, 2013, 15, 54. (link: http://pubs.acs.org/doi/abs/10.1021/ol303085q).
  5. Serge-Mithérand Tengho Toguem, Imran Malik, Munawar Hussain, Jamshed Iqbal, Alexander Villinger, Peter Langer. Synthesis of functionalized benzothiophenes and dibenzothiophenes by twofold Heck and sub-sequent 6π-electrocyclization reactions of 2,3-dibromothiophenes and 2,3-dibromobenzothiophenes, Tetrahedron, 2012, 69, 160. (link: http://www.sciencedirect.com/science/article/pii/S0040402012016109).
  6. Munawar Hussain, Tran Van Sung, and Peter Langer. Domino Twofold Heck / 6p-Electrocyclization Reactions of 1,2-Dihaloalkenes, Synlett., 2012, 23, 2735. (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1317192).
  7. Zahid Hassan, Munawar Hussain, Alexander Villinger, Peter Langer. Synthesis of aryl-substituted naphthalenes by chemoselective Suzuki–Miyaura reactions of bromo-trifluoromethanesulfonyloxy-naphthalenes. Influence of steric and electronic parameters. Tetrahedron, 2012, 68, 6305. (link: http://www.sciencedirect.com/science/article/pii/S0040402012007065).
  8. Rasheed Ahmad Khera, Munawar Hussain, Nguyen Thai Hung, Nadi Eleya, Holger Feist, Alexander Villinger and Peter Langer, Regioselective Arylation and Alkynylation of 2,3-Dibromo-1H-inden-1-one bySuzuki-Miyaura and Sonogashira Cross-Coupling Reactions. Helv. Chim. Acta 2012, 95, 69 (link: http://onlinelibrary.wiley.com/doi/10.1002/hlca.201100315/full)
  9. Rasheed Ahmad Khera,  Asad Ali,  Munawar Hussain, Muhammad Farooq Ibad,  Alexander Villinger and Prof. Peter Langer. Site-Selective Suzuki–Miyaura and Sonogashira Cross Coupling Reactions of the Bis(triflate) of 2,4′-Bis(hydroxy)diphenyl Sulfone. ChemCatChem 2012, 4, 356 (link: http://onlinelibrary.wiley.com/doi/10.1002/cctc.201100257/full).
  10. Rasheed Ahmad Khera, Asad Ali, Hummera Rafique, Munawar Hussain, Jovana Tatar, Aamer Saeed, Alexander Villinger, Peter Langer. Suzuki–Miyaura reactions of N-protected tribromopyrazoles. Efficient and site-selective synthesis of 3,4,5-triaryl-pyrazoles, 3,5-diaryl-4-bromopyrazoles and 5-aryl-3,4-dibromopyrazoles. Tetrahedron 2011, 67, 5244 (link: http://www.sciencedirect.com/science/article/pii/S0040402011007022)
  11. Munawar Hussain, Serge-Mithérand Tengho Toguem, Rasheed Ahmad, Đặng Thanh Tùng, Ingo Knepper, Alexander Villinger, Peter Langer. Synthesis of carbazoles and 1,2-dihydrocarbazoles by domino ‘twofold Heck/6π-electrocyclization’ reactions of di-, tri- and tetrabromoindoles. Tetrahedron2011, 67, 5304 (link: http://www.sciencedirect.com/science/article/pii/S0040402011006685)
  12. Dhafer Saber Zinad, Munawar Hussain, Omer Adeeb Akrawi, Alexander Villinger, Peter Langer. Site-selective Suzuki–Miyaura reactions of the bis(triflate) of 1,3-dihydroxythioxanthone. Tetrahedron Lett. 2011, 52, 1093( link:  http://www.sciencedirect.com/science/article/pii/S0040403910023403).
  13. Zahid Hassan, Munawar Hussain,Peter Langer. Synthesis of 1,2-Diarylnaphthalenes by Chemoselective Suzuki-Miyaura Reactions of 2-Bromo-1-(trifluoromethanesulfonyloxy)naphthalene. Synlett. 2011, 13, 1827 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1260955).
  14. Dhafer Saber Zinad,Munawar Hussain, Alexander Villinger, Peter Langer. Site-selective Synthesis of Arylated Indenones by Suzuki-Miyaura Cross-Coupling Reactions of 2,3,5-Tribromoinden-1-one.Eur. J. Org. Chem2011, 22, 4212- 4221 (link: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201100313/abstract)
  15. Omer Adeeb Akrawi, Munawar Hussain, Peter Langer.Site-selective Suzuki-Miyaura reactions of the bis(triflate) of 1,3-dihydroxyanthraquinone. Tetrahedron Lett. 2011, 52,1093-1095 (link: http://www.sciencedirect.com/science/article/pii/S0040403910023403).
  16. Ghazwan Ali Salman, Ahmad Mahal, Mohanad Shkoor, Munawar Hussain, Alexander Villinger, Peter Langer. Regioselective Suzuki–Miyaura reactions of the bis(triflate) of 1,2,3,4-tetrahydro-9,10-dihydroxyanthracen-1-one. Tetrahedron Lett. 2011,52, 392 (link: http://www.sciencedirect.com/science/article/pii/S0040403910020629).
  17. Ibad, Muhammad Farooq; Eleya, Nadi; Obaid-Ur-Rahman, Abid; Mahal, Ahmed; Hussain, Munawar; Villinger, Alexander; Langer, Peter. Site-Selective Suzuki-Miyaura Reactions of 1,4- and 3,5-Bis(trifluoromethylsulfonyloxy)-2-naphthoates. Synthesis 2011, 13, 2101 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1260054).
  18. Ghazwan Ali Salman, Munawar Hussain, Viktor O. Iaroshenko, Alexander Villinger, Peter Langer. Domino C-N coupling / annulation versus C-N coupling / hydroamination of 2-alkynyl-3-bromobenzothiophenes and 2-alkynyl-3-bromothiophenes. Highly efficient synthesis of benzothieno[3,2-b]quinolines and thieno[3,2-b]pyrroles. Adv. Synth. & Cat.2011, 353 (link: http://onlinelibrary.wiley.com/doi/10.1002/adsc.201000709/abstract).
  19. Ghazwan Ali Salman, Munawar Hussain, Alexander Villinger, Peter Langer. Site-Selective Suzuki-Miyaura Reactions of the Bis(triflate) of 5,10-dihydroxy-11H-benzo[b]fluoren-11-one. Synlett. 2011,3031.
  20. Munawar Hussain, Rasheed Ahmed Khera, Nguyen Thai Hung,Peter Langer. Site-Selective Suzuki-Miyaura Cross-Coupling Reactions of 2,3,4,5-Tetrabromofuran. Org. & Biomol. Chem. 2010, 9, 370 (link: http://pubs.rsc.org/en/Content/ArticleLanding/2011/OB/c0ob00695e#!divAbstract).
  21. Rasheed Ahmad Khera, Munawar Hussain, Rasheed Ahmad, Alexander Villinger, Aamer Saeed,Christine Fischer, Peter Langer. Synthesis of fluorinated 2,3-dihydropyran-4-ones by cyclocondensation of 1,3-dicarbonyl dianions with aldehydes. Jr. Fluorine Chemistry 2010, 131, 892 (link: http://www.sciencedirect.com/science/article/pii/S0022113910001533).
  22. Ghazwan Ali Salman, Asad Ali, Munawar Hussain, Rasheed Ahmed Khera, Peter LangerSynthesis of Functionalized Benzofurans by a Double Heck Reaction of 2,3-Dibromofurans and Subsequent 6π-Electrocyclization / Dehydrogenation. Synthesis 2011, 14, 2208 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1260666).
  23. Munawar Hussain, Nguyen Thai Hung,Rasheed Ahmed Khera, Peter Langer. Site-selective Suzuki–Miyaura reactions of 2,3-dibromo-1H-inden-1-one. Tetrahedron Lett. 2010, 52, 184 (link: http://www.sciencedirect.com/science/article/pii/S0040403910019027).
  24. Imran Malik, Munawar Hussain, Nguyen Thai Hung, Alexander Villinger, Peter Langer. Synthesis of 7,8-Diarylflavones by Site-Selective Suzuki-Miyaura Reactions. Synlett. 2010, 15, 2244 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1258043).
  25. Munawar Hussain, Nguyen Thai Hung, Rasheed Ahmad Khera, Imran Malik, Dhafer Saber Zinad, Peter Langer.Synthesis of Aryl-Substituted Pyrimidines by Site-Selective Suzuki-Miyura Cross-Coupling Reactions of 2,4,5,6-Tetrachloropyrimidines. Adv. Synth. & Cat.2010, 1429 (link: http://onlinelibrary.wiley.com/doi/10.1002/adsc.201000020/abstract).
  26. Asad Ali, Rasheed Ahmad Khera,Munawar Hussain,Jovana Tatar, Alexander Villinger, Peter Langer. Synthesis of Arylated Pyrazoles by Site-Selective Suzuki-Miyaura Reactions of Tribromopyrazoles. Synlett. 2010, 13, 1923 (link: https://www.thieme-connect.de/DOI/DOI?10.1055/s-0030-1258489).
  27. Asad Ali,Munawar Hussain, Imran Malik, Christine Fischer, Peter Langer. Double Heck Cross-Coupling ominated Pyridines. Helv. Chim. Acta 2010, 93, 1764 (link: http://onlinelibrary.wiley.com/doi/10.1002/hlca.201000108/abstract).
  28. Nguyen Thai Hung, Munawar Hussain, Imran Malik, Alexander Villinger, Peter Langer. Site-selective Suzuki cross-coupling reactions of 2,3-dibromobenzofuran. Tetrahedron Lett. 2010, 51, 2420 (link: http://www.sciencedirect.com/science/article/pii/S0040403910003527).
  29. Olumide Fatunsin, Mohanad Shkoor, Abdolmajid Riahi, Munawar Hussain, Alexander Villinger, Christine Fischer and Peter Langer. Regioselective Synthesis of 5-(Arylsulfanyl)- and 5-(Benzylsulfanyl)-6-phenylsalicylates by One-Pot Cyclizations of 1,3-Bis(silyloxy)buta-1,3-dienes with 2-(Arylsulfanyl)- and 5-(Benzylsulfanyl)-3-ethoxy-1-phenylprop-2-en-1-ones.Helv. Chim. Acta 2010, 93, 1610 (link: http://onlinelibrary.wiley.com/doi/10.1002/hlca.200900393/full).
  30. Asad Ali, Rasheed Ahmad Khera, Muhammad Farooq Ibad, Munawar Hussain, Peter Langer. Synthesis of Bis(diaryl)sulfones by Site-Selective Suzuki-Miyaura Reactions of 2,4′-Bis(trifluoromethylsulfonyloxy)diphenylsulfone Synlett. 2010, 5, 0731 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1219343).
  31. Muhammad Farooq Ibad, Munawar Hussain, Obaid-Ur-Rahman Abid, Asad Ali, Ihsan Ullah, Dhafer Saber Zinad, Peter Langer. One-Pot Synthesis of Unsymmetrical 2,3-Diarylindoles by Site-Selective Suzuki-Miyaura Reactions of N-Methyl-2,3-dibromoindole Synlett. 2010, 411 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1219201).
  32. Imran Malik, Munawar Hussain, Asad Ali, Serge-Mithérand Tengho Toguem, Fatima Z. Basha, Christine Fischer, Peter Langer. Synthesis of 2,3-disubstituted pyrazines and quinoxalines by Heck cross-coupling reactions of 2,3-dichloropyrazine and 2,3-dichloroquinoxaline. Influence of the temperature on the product distribution.Tetrahedron 2010, 66, 1637-1642 (link: http://www.sciencedirect.com/science/article/pii/S0040402010000360).
  33. Munawar Hussain, Dhafer Saber Zinad, Ghazwan Ali Salman, Muhammad Sharif, Alexander Villinger, Peter Langer. Efficient Synthesis of Functionalized Anthraquinones by Domino Twofold Heck-6π-Electrocyclization Reactions of 2,3-Dibromonaphthoquinone. Synlett. 2010, 276 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1218560).
  34. Munawar Hussain, Imran Malik, Alexander Villinger, Peter Langer. Efficient Synthesis of Functionalized 2,3-Di(alkenyl)benzothiophenes and Dibenzothiophenes Based on the First Heck Reactions of 2,3-Di- and 2,3,6-Tribromobenzothiophene. Synlett. 2009, 2691 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1217975).
  35. Serge-Mithérand Tengho Toguem, Munawar Hussain, Imran Malik, Alexander Villinger, Peter Langer. Synthesis of functionalized benzothiophenes by twofold Heck and subsequent 6π-electrocyclization reactions of 2,3-dibromothiophene. Tetrahedron Lett. 2009, 50, 4962 (link: http://www.sciencedirect.com/science/article/pii/S0040403909012118).
  36. Inam Iqbal, Muhammad Imran, Nasir Rasool, Muhammad A. Rashid, Munawar Hussain, Alexander Villinger, Christine Fischer, Peter Langer. Synthesis of functionalized 2-(arylthio)benzoates by formal [3+3] cyclizations of 3-arylthio-1-silyloxy-1,3-butadienes with 3-silyloxy-2-en-1-ones and 1,3-diacylcyclopropanes. Tetrahedron 2009, 65, 7562 (link: http://www.sciencedirect.com/science/article/pii/S0040402009009958).
  37. Ihsan Ullah, Rasheed Ahmad Khera, Munawar Hussain, Alexander Villinger, Peter Langer. Synthesis of tetraaryl-p-benzoquinones by Suzuki–Miyaura cross-coupling reactions of tetrabromo-p-benzoquinone.Tetrahedron Lett. 2009, 50, 4651-4653 (link: http://www.sciencedirect.com/science/article/pii/S0040403909011393).
  38. Munawar Hussain, Nguyen Thai Hung, Peter Langer. Efficient synthesis of functionalized dibenzofurans by domino ‘twofold Heck/6π-electrocyclization’ reactions of 2,3-di- and 2,3,5-tribromobenzofuran. Tetrahedron Lett. 2009, 50, 3929 (link: http://www.sciencedirect.com/science/article/pii/S0040403909008892).
  39. Munawar Hussain, Tung T. Dang, Peter Langer. Synthesis of Carbazoles and 1,2-Dihydrocarbazoles by Domino Twofold Heck / 6p-Electrocyclization Reactions of Di- and Tribromo-N-methylindoles. Synlett. 2009, 1822 (link: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1217357).
  40. Munawar Hussain, Vanessa Ahmed, Bryan Hill, Zaheer Ahmed, Scott D. Taylor. A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition Bioorganic & Medicinal Chemistry, 2008, 16, 6764 (link: http://www.sciencedirect.com/science/article/pii/S096808960800504X).
  41. Munawar Hussain, Durey Nayab Zahra, Abdul Malik, Asma Ejaz, Hina Siddiqui, Muhammad Iqbal Choudhary, and Zaheer Ahmed. Flavonoidal C-Glycosides from Abutilon Pakistanicum Heterocycles 2008, 75, 645 (link:https://www.heterocycles.jp/newlibrary/payments/form/02490/PDF).
  42. Munawar Hussain, Durey Nayab Zahra, S. M. Shakil Hussain, Ejaz Ahmed, Ijaz Ahmad, Abdul Malik, Zaheer Ahmed. ‘Structure determination of new steroids from Abutilon pakistanicum by NMR techniques Magn. Reson. Chem., 2008, 46, 274 (link: http://onlinelibrary.wiley.com/wol1/doi/10.1002/mrc.2139/abstract).
  43. Munawar Hussain, Durey Nayab Zahra, Dildar Ali, Abdul Malik and Zaheer Ahmed. Chemical Constituents from Abutilon Species J. Chem. Soc. Pak. 2005, 26, 327 (link: http://jcsp.org.pk/ArticleUpload/864-3629-1-RV.pdf).

  • Synthesis of chemicals important in the Drug Development, Pesticides & Materials etc., Catalysis & Research Mehtodology, Development of Local Chemical Manufacturing Facilities. 

  • Carl Tryggers Stiftels for Post Doc., Umea University, Sweden.
  • Mecklenburg-State Scholarship, University of Rostock, Rostock, Germany
  • HEC Pakistan Split Ph.D. Scholarship, under Development of High Level S&T Manpowr at Canada.

  • Head of Department, Department of Chemistry
  • Academic Council – member
  • Center for Advanced Organic Synthessi & Technology Development – Leader
  • Convocation committee - member
  • Scholarship Committee - memebr